Nitrile-containing pharmaceuticals: target, mechanism of action, and their SAR studies-Reference-Cited by-同舟云学术

Nitrile-containing pharmaceuticals: target, mechanism of action, and their SAR studies

Published:2021 Issue:10 Volume:12 Page:1650-1671
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

Wang Xi¹,Wang Yuanxun²,Li Xuemin¹,Yu Zhenyang¹,Song Chun³,Du Yunfei¹^ORCID

Affiliation:

1. School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China

2. National Institution of Biological Sciences, Beijing, No. 7 Science Park Road, Zhongguancun Life Science Park, Beijing 102206, China

3. State Key Laboratory of Microbial Technology, Shandong University, Qingdao City, Shandong Province, 266237, China

Abstract

This review summarizes versatile nitrile-containing drugs in the following aspects: target, mechanism of action and their structure activity relationship, and categorizes these drugs based on their target diseases.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/MD/D1MD00131K

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