Enabling organometallic libraries by flow: a tale of two metals-Reference-Cited by-同舟云学术

登录注册会员服务联系我们

Enabling organometallic libraries by flow: a tale of two metals

Published:2024 Issue:7 Volume:9 Page:1656-1665
ISSN:2058-9883
Container-title:Reaction Chemistry & Engineering
language:en
Short-container-title:React. Chem. Eng.

Author:

Maddox Daniel¹^ORCID,Guetzoyan Lucie¹,Walmsley Lee¹^ORCID

Affiliation:

1. Vernalis (R&D) Ltd, Granta Park, Great Abington, Cambridge, CB21 6GB, UK

Abstract

We present, to our knowledge, the first library synthesised from on-demand Grignard reagents: a 76-member library. We also present a matrix library of 21 Negishi products, both libraries giving a success rate of >90% at the organometallic step.

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RE/D3RE00677H

Reference19 articles.

1. Recent Developments in Negishi Cross-Coupling Reactions

2. Expanding the Medicinal Chemist Toolbox: Comparing Seven C(sp2)–C(sp3) Cross-Coupling Methods by Library Synthesis

3. Recent advances in Kumada-Tamao-Corriu cross-coupling reaction catalyzed by different ligands

4. The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP