DABCO-mediated isocyanide-based multicomponent reaction: synthesis of highly substituted cyclopentenes

Author:

Wen Li-Rong1234,Lan Ming-Chao1234,Yuan Wen-Kui1234,Li Ming12345

Affiliation:

1. State Key Laboratory Base of Eco-Chemical Engineering

2. College of Chemistry and Molecular Engineering

3. Qingdao University of Science and Technology

4. Qingdao 266042, P. R. China

5. State Key Laboratory of Institute of Elemento-organic Chemistry

Abstract

Highly substituted cyclopentenes can be accessed rapidly from isocyanides, aldehydes and malononitrile or ethyl cyanoacetate (AB2C2) using DABCO as a catalyst under solvent-free conditions at 40 °C within 30 min.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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