A label-free screening approach targeted protease-activated receptor 1 based on dynamic mass redistribution in living cells
Author:
Affiliation:
1. State Key Laboratory of Natural Medicines
2. China Pharmaceutical University
3. Nanjing 210009
4. P. R. China
5. U-Pharm Laboratories LLC
6. Parsippany
7. USA
Abstract
Protease-activated receptor 1 (PAR-1) antagonists strongly inhibit thrombin-induced platelet aggregation and are proved to be effective as anti-thrombotic drugs.
Funder
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/RA/C7RA07927C
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