Dietary lipoic acid alleviates autism-like behavior induced by acrylamide in adolescent mice: the potential involvement of the gut

Dietary lipoic acid alleviates autism-like behavior induced by acrylamide in adolescent mice: the potential involvement of the gut–brain axis

Published:2024 Issue:7 Volume:15 Page:3395-3410
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Ye Jin¹,Fan Hua¹,Shi Renjie¹,Song Ge²,Wu Xiaoning¹,Wang Danna¹,Xia Bing¹,Zhao Zhenting¹,Zhao Beita¹^ORCID,Liu Xuebo¹^ORCID,Wang Yutang¹^ORCID,Dai Xiaoshuang²

Affiliation:

1. College of Food Science and Engineering, Northwest A&F University, Yangling, Shaanxi, China

2. BGI Institute of Applied Agriculture, BGI-Shenzhen, Shenzhen, China

Abstract

Lipoic acid (LA) ameliorated acrylamide (ACR)-induced social impairment in adolescent mice. Lipoic acid (LA) reshaped gut microbiota and its metabolites. Lipoic acid (LA) regulated serum amino acid level.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/FO/D3FO05078E

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