Hypoglycemic and lipid lowering effects of theaflavins in high-fat diet-induced obese mice-Reference-Cited by-同舟云学术

Hypoglycemic and lipid lowering effects of theaflavins in high-fat diet-induced obese mice

Published:2021 Issue:20 Volume:12 Page:9922-9931
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Cai Xiaqiang¹²,Liu Zenghui³,Dong Xu¹²,Wang Ying¹²,Zhu Luwei¹²,Li Mengli¹²,Xu Yan¹²^ORCID

Affiliation:

1. State Key Laboratory of Tea Plant Biology and Utilization/Key Laboratory of Tea Biology and Tea Processing of Ministry of Agriculture/Anhui Provincial Laboratory of Tea Plant Biology and Utilization, Anhui Agricultural University, Hefei, China

2. International Joint Laboratory on Tea Chemistry and Health Effects of Ministry of Education, Hefei, China

3. Anhui Academy of Medical Sciences, Hefei 230061, China

Abstract

TFs, TF1, TF2a and TF3 administered to HFD mice not only decreased the level of blood glucose and HOMA-IR but also activated the SIRT6/AMPK/SREBP-1/FASN pathway to inhibite synthesis and accumulation of the lipids in the liver to ameliorate obesity.

Funder

Natural Science Foundation of Anhui Province

Earmarked Fund for China Agriculture Research System

Key Technologies Research and Development Program of Anhui Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/FO/D1FO01966J

Reference36 articles.

1. Six types of tea reduce high-fat-diet-induced fat accumulation in mice by increasing lipid metabolism and suppressing inflammation