Synthesis, cytotoxic evaluation and DNA binding study of 9-fluoro-6H-indolo[2,3-b]quinoxaline derivatives-Reference-Cited by-同舟云学术

Synthesis, cytotoxic evaluation and DNA binding study of 9-fluoro-6H-indolo[2,3-b]quinoxaline derivatives

Published:2017 Issue:66 Volume:7 Page:41869-41879
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Gu Zhenyu¹²³⁴⁵,Li Yanci¹²³⁴⁵,Ma Songliang¹²³⁴⁵,Li Shenghui¹²³⁴⁵^ORCID,Zhou Guoqiang¹²³⁴⁵,Ding Shan¹²³⁴⁵,Zhang Jinchao¹²³⁴⁵^ORCID,Wang Shuxiang¹²³⁴⁵,Zhou Chuanqi¹²³⁴⁵^ORCID

Affiliation:

1. Key Laboratory of Chemical Biology of Hebei Province

2. Key Laboratory of Medicinal Chemistry and Molecular Diagnosis

3. Ministry of Education

4. College of Chemistry & Environmental Science

5. Hebei University

Abstract

New quaternary ammonium salts of 9-fluoro-6H-indolo[2,3-b] derivatives were synthesized. These compounds possessed enhanced DNA binding ability and improved antitumor activity.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/RA/C7RA08138C

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