Design, semi-synthesis and molecular docking of new antibacterial and antibiofilm triazole conjugates from hydroxy-triterpene acids and fluoroquinolones-Reference-Cited by-同舟云学术

Design, semi-synthesis and molecular docking of new antibacterial and antibiofilm triazole conjugates from hydroxy-triterpene acids and fluoroquinolones

Published:2023 Issue:34 Volume:47 Page:15973-15986
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Boulila Besma¹²,Horchani Mabrouk¹,Duval Raphael³,Othman Mohamed²,Daïch Adam²^ORCID,Ben Jannet Hichem¹,Romdhane Anis¹,Lawson Ata Martin²^ORCID

Affiliation:

1. University of Monastir, Faculty of Sciences of Monastir, Laboratory of Heterocyclic Chemistry, Natural Products and Reactivity (LR11ES39), Team: Medicinal Chemistry and Natural Products, Avenue of Environment, 5019 Monastir, Tunisia

2. Normandie Univ, UNILEHAVRE, URCOM, EA 3221, INC3M, FR 3038 CNRS, F-76600 Le Havre, France

3. Université de Lorraine, CNRS, L2CM, F-54000 Nancy, France

Abstract

Maslinic acid- and oleanolic acid-based hyrids with potent antibacterial and antibiofilm activities were designed and semi-synthesized from pentacyclic triterpene acids isolated from olive oil manufacturing solid waste.

Funder

Ministère de l’Enseignement Supérieur et de la Recherche Scientifique

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/NJ/D3NJ02922K

Reference49 articles.

1. Pentacyclic triterpene acids in olives

2. 3-b-Hydroxyolean-12-en-28-oic Acid (Oleanolic Acid)

3. 2-a, 3-b-Dihydroxyolean-12-en-28-oic Acid (Maslinic Acid)

4. Bioactive Properties of the Main Triterpenes Found in Olives, Virgin Olive Oil, and Leaves of Olea europaea

5. Oleanolic acid

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