Boron clusters as a platform for new materials: composites of nucleic acids and oligofunctionalized carboranes (C2B10H12) and their assembly into functional nanoparticles

Author:

Kaniowski Damian1234ORCID,Ebenryter-Olbinska Katarzyna1234ORCID,Kulik Katarzyna1234ORCID,Janczak Slawomir5264,Maciaszek Anna1234ORCID,Bednarska-Szczepaniak Katarzyna5264ORCID,Nawrot Barbara1234ORCID,Lesnikowski Zbigniew5264ORCID

Affiliation:

1. Centre of Molecular and Macromolecular Studies

2. Polish Academy of Sciences

3. 90-363 Lodz

4. Poland

5. Institute of Medical Biology

6. 92-232 Lodz

Abstract

The building blocks based on boron cluster spanning two short DNA adapters assemble into functional nanoparticles due to the formation of DNA helices. They offer dual-action therapeutic potential, e.g., in the BNCT and gene expression regulation.

Funder

Narodowe Centrum Nauki

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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