Base-catalysed reductive relay hydroboration of allylic alcohols with pinacolborane to form alkylboronic esters

Author:

Wang Zi-Chao12345,Shen Di12345,Gao Jian12345,Jia Xian1234,Xu Youjun1234ORCID,Shi Shi-Liang56789ORCID

Affiliation:

1. School of Pharmaceutical Engineering, and Key Laboratory of Structure-Based Drug Design & Discovery (Ministry of Education)

2. Shenyang Pharmaceutical University

3. Shenyang 110016

4. China

5. State Key Laboratory of Organometallic Chemistry

6. Center for Excellence in Molecular Synthesis

7. Shanghai Institute of Organic Chemistry

8. Chinese Academy of Sciences

9. Shanghai 200032

Abstract

A novel reductive relay hydroboration of allylic alcohols with pinacolborane using nBuLi as an efficient initiator is reported.

Funder

National Natural Science Foundation of China

Chinese Academy of Sciences

Ministry of Education of the People's Republic of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Reference78 articles.

1. H. C. Brown , Hydroboration, Benjamin/Cummings, Reading, Massachusetts , 2nd edn, 1980

2. D. S. Matteson , Stereodirected synthesis with organoboranes , Springer Science & Business Media , 2012

3. D. G. Hall , Boronic Acids: Preparation and Applications in Organic Synthesis , Medicine and Materials Wiley-VCH , Weinheim , 2011

4. Organoboranes for synthesis - substitution with retention

5. Catalytic Asymmetric Hydroboration: Recent Advances and Applications in Carbon−Carbon Bond‐Forming Reactions

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