Chalcone Mannich base derivatives: synthesis, antimalarial activities against <i>Plasmodium knowlesi</i>, and molecular docking analysis-Reference-Cited by-同舟云学术

Chalcone Mannich base derivatives: synthesis, antimalarial activities against Plasmodium knowlesi, and molecular docking analysis

Published:2023 Issue:51 Volume:13 Page:36035-36047
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Syahri Jufrizal¹,Hilma Rahmiwati¹,Ali Amatul Hamizah²,Ismail Norzila³^ORCID,Yee Ling Ng⁴,Nurlaili ¹,Nurohmah Beta Achromi⁵,Agustar Hani Kartini⁶,Ling Lau Yee⁴,Latip Jalifah²^ORCID

Affiliation:

1. Department of Chemistry, Universitas Muhammadiyah Riau, Jalan Tuanku Tambusai Ujung, Pekanbaru, Indonesia

2. Department of Chemical Sciences, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor, Malaysia

3. Department of Pharmacology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia

4. Department of Parasitology, Faculty of Medicine, Universiti Malaya, 50603, Kuala Lumpur, Malaysia

5. Department of Chemistry, Universitas Gadjah Mada, Jalan Kaliurang Sekip Utara Bulaksumur 21, 55281, Yogyakarta, Indonesia

6. Department of Earth Science and Environment, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor, Malaysia

Abstract

Research on the antimalarial effect of aminoalkyl chalcone derivatives against Plasmodium falciparum and Plasmodium knowlesi has bolstered efforts in drug discovery to combat cases of drug resistance.

Funder

Pusat Pengurusan Penyelidikan dan Instrumentasi

Kementerian Pendidikan, Kebudayaan, Riset, dan Teknologi

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D3RA05361J

Reference57 articles.

1. World Health Organization (WHO) , World Malaria Report , Geneva , 2022 , https://www.who.int/teams/global-malaria-programme/reports/world-malaria-report-2022

2. Ministry of Health (MOH) , Tren Kasus Malaria Menurun , Indonesia , 2022 , https://www.kemkes.go.id/article/view/21042300004/tren-kasus-malaria-menurun.html , accessed on 30 June 2022

3. Na+ Regulation in the Malaria Parasite Plasmodium falciparum Involves the Cation ATPase PfATP4 and Is a Target of the Spiroindolone Antimalarials

4. Spread of Artemisinin Resistance in Plasmodium falciparum Malaria

5. Understanding artemisinin resistance