Soyasaponins A1 and A2 exert anti-atherosclerotic functionalities by decreasing hypercholesterolemia and inflammation in high fat diet (HFD)-fed ApoE−/− mice
Author:
Affiliation:
1. Department of Nutrition and Food Hygiene
2. Guangdong Provincial Key Laboratory of Tropical Disease Research
3. School of Public Health
4. Southern Medical University
5. Guangzhou 510515
Abstract
To the best of our knowledge, this study firstly shows that soyasaponins (A1 & A2) exhibit antiatherosclerotic bioactivities by improving the serum lipid profile and reducing TLR4-/MyD88-/NF-κB-mediated inflammations in high fat diet-fed ApoE−/− mice.
Funder
National Natural Science Foundation of China
Natural Science Foundation of Guangdong Province
Southern Medical University
Publisher
Royal Society of Chemistry (RSC)
Subject
General Medicine,Food Science
Link
http://pubs.rsc.org/en/content/articlepdf/2020/FO/C9FO02654A
Reference77 articles.
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2. Atherosclerosis
3. Inflammation in atherosclerosis
4. Oxidative Stress in Atherosclerosis
5. Nutrition and Atherosclerosis
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