A comprehensive analysis in one run – in-depth conformation studies of protein–polymer chimeras by asymmetrical flow field-flow fractionation-Reference-Cited by-同舟云学术

A comprehensive analysis in one run – in-depth conformation studies of protein–polymer chimeras by asymmetrical flow field-flow fractionation

Published:2021 Issue:41 Volume:12 Page:13848-13856
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Kaupbayeva Bibifatima¹²,Murata Hironobu²,Matyjaszewski Krzysztof²³,Russell Alan J.¹²³⁴,Boye Susanne⁵^ORCID,Lederer Albena⁵⁶^ORCID

Affiliation:

1. Department of Biological Sciences, Carnegie Mellon University, 4400 Fifth Avenue, Pittsburgh, PA 15213, USA

2. Center for Polymer-Based Protein Engineering, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, PA 15213, USA

3. Department of Chemistry, Carnegie Mellon University, 4400 Fifth Avenue, Pittsburgh, PA 15213, USA

4. Department of Chemical Engineering, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, PA 15213, USA

5. Center Macromolecular Structure Analysis, Leibniz-Institut für Polymerforschung Dresden e.V., Hohe Straße 6, Dresden 01069, Germany

6. Stellenbosch University, Department of Chemistry and Polymer Science, Private Bag X1, Matieland 7602, South Africa

Abstract

Precise characterization of structural parameters and their polydispersities of protein–polymer conjugates is performed with rapid analysis using asymmetrical flow field-flow fractionation coupled with multiple detectors.

Funder

Defense Threat Reduction Agency

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/SC/D1SC03033G

Reference40 articles.

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