RNA ligation of very small pseudo nick structures by T4 RNA ligase 2, leading to efficient production of versatile RNA rings-Reference-Cited by-同舟云学术

RNA ligation of very small pseudo nick structures by T4 RNA ligase 2, leading to efficient production of versatile RNA rings

Published:2019 Issue:15 Volume:9 Page:8620-8627
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Cheng Kai¹²³⁴,An Ran¹²³⁴⁵^ORCID,Cui Yixiao¹²³⁴^ORCID,Zhang Yaping¹²³⁴,Han Xutiange¹²³⁴,Sui Zhe¹²³⁴,Chen Hui¹²³⁴,Liang Xingguo¹²³⁴⁵^ORCID,Komiyama Makoto¹²³⁴

Affiliation:

1. College of Food Science and Engineering

2. Ocean University of China

3. Qingdao 266003

4. China

5. Laboratory for Marine Drugs and Bioproducts

Abstract

T4 Rnl2 ligates ssRNA via nick-like structures, leading to efficient production of versatile RNA rings for various applications.

Funder

China Postdoctoral Science Foundation

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/RA/C9RA01513B

Reference34 articles.

1. Therapeutic miRNA and siRNA: Moving from Bench to Clinic as Next Generation Medicine

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