Clinical experiences with systemically administered siRNA-based therapeutics in cancer
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology,General Medicine
Link
http://www.nature.com/articles/nrd4685.pdf
Reference92 articles.
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3. Vaishnaw, A. K. et al. A status report on RNAi therapeutics. Silence 1, 14 (2010).
4. de Fougerolles, A., Vornlocher, H.-P., Maraganore, J. & Lieberman, J. Interfering with disease: a progress report on siRNA-based therapeutics. Nat. Rev. Drug Discov. 6, 443–453 (2007).
5. Sepp-Lorenzino, L. & Ruddy, M. K. Challenges and opportunities for local and systemic delivery of siRNA and antisense oligonucleotides. Clin. Pharmacol. Ther. 84, 628–632 (2008).
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