An efficient green protocol for the preparation of acetoacetamides and application of the methodology to a one-pot synthesis of Biginelli dihydropyrimidines. Expansion of dihydropyrimidine topological chemical space
Author:
Affiliation:
1. Instituto de Química
2. Universidade Federal do Rio de Janeiro
3. Centro de Tecnologia
4. 21949-909 Rio de Janeiro
5. Brazil
Abstract
A one pot synthesis of Biginelli dihydropyrimidines. The novel use of the amino acids allows topological diversification of the chemical space.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA14355A
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