Selenium species-dependent toxicity, bioavailability and metabolic transformations in Caenorhabditis elegans

Author:

Rohn Isabelle12345,Marschall Talke Anu12345,Kroepfl Nina678910ORCID,Jensen Kenneth Bendix678910,Aschner Michael1112131415,Tuck Simon16171819,Kuehnelt Doris678910ORCID,Schwerdtle Tanja12345ORCID,Bornhorst Julia12345ORCID

Affiliation:

1. Department of Food Chemistry

2. Institute of Nutritional Science

3. University of Potsdam

4. 14558 Nuthetal

5. Germany

6. Institute of Chemistry

7. Analytical Chemistry

8. NAWI Graz

9. University of Graz

10. 8010 Graz

11. Department of Molecular Pharmacology

12. Neuroscience, and Pediatrics

13. Albert Einstein College of Medicine

14. 10461 Bronx

15. USA

16. Umeå Centre for Molecular Medicine

17. Umeå University

18. 90187 Umeå

19. Sweden

Abstract

Depending strongly on the ingested selenium (Se) form differences in toxicity, bioavailability as well as metabolism occur in C. elegans.

Funder

Deutsche Forschungsgemeinschaft

National Institute of Environmental Health Sciences

Austrian Science Fund

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Metals and Alloys,Biochemistry,Biomaterials,Biophysics,Chemistry (miscellaneous)

Reference50 articles.

1. Selenium and human health

2. European Commission, Opinion of the Scientific Committee on Food on the tolerable upper intake level of selenium, 2000

3. Selenium and Human Health: Witnessing a Copernican Revolution?

4. Effect of Selenium and Vitamin E on Risk of Prostate Cancer and Other Cancers

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