Synthesis, structures, and DNA and protein binding of ruthenium(ii)-p-cymene complexes of substituted pyridylimidazo[1,5-a]pyridine: enhanced cytotoxicity of complexes of ligands appended with a carbazole moiety-Reference-Cited by-同舟云学术

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Synthesis, structures, and DNA and protein binding of ruthenium(ii)-p-cymene complexes of substituted pyridylimidazo[1,5-a]pyridine: enhanced cytotoxicity of complexes of ligands appended with a carbazole moiety

Published:2016 Issue:115 Volume:6 Page:114143-114158
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Khamrang Themmila¹²³⁴,Kartikeyan Radhakrishnan¹⁵⁶⁷⁴,Velusamy Marappan¹²³⁴,Rajendiran Venugopal¹⁵⁶⁷⁴,Dhivya Rajakumar⁸⁹¹⁰⁴,Perumalsamy Balaji⁸⁹¹⁰⁴,Akbarsha Mohammad Abdulkadher⁸⁹¹⁰⁴,Palaniandavar Mallayan¹⁹¹¹⁴

Affiliation:

1. Department of Chemistry

2. North Eastern Hill University

3. Shillong 793022

4. India

5. School of Basic and Applied Sciences

6. Central University of Tamil Nadu

7. Thiruvarur 610101

8. Mahatma Gandhi-Doerenkamp Center for Alternatives to Use of Animals in Life Science Education

9. Bharathidasan University

10. Tiruchirappalli 620024

11. Tiruchirapalli 620024

Abstract

The cytotoxicity of ruthenium-arene complexes appended with carbazole moiety correlates with their DNA binding ability.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA23663D

Reference107 articles.

1. New metal complexes as potential therapeutics

2. NKP-1339, the first ruthenium-based anticancer drug on the edge to clinical application

3. Ruthenium Antimetastatic Agents

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