Programmable one-pot synthesis of heparin pentasaccharides enabling access to regiodefined sulfate derivatives
Author:
Affiliation:
1. Department of Chemistry
2. The Scripps Research Institute
3. USA
4. The Genomics Research Center
5. Academia Sinica
Abstract
We report the design of building blocks with optimized reactivities for the programmable one-pot synthesis of heparin pentasaccharides with regiodefined sulfation patterns.
Funder
Academia Sinica
National Science Foundation
National Institutes of Health
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/SC/C8SC01743C
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