Synthesis of 2-trifluoromethyl indoles via visible-light induced intramolecular radical cyclization
Author:
Affiliation:
1. School of Chemistry and Chemical Engineering
2. Sun Yat-Sen University
3. Guangzhou 510275
4. China
Abstract
A visible-light induced intramolecular radical cyclization is described. The reaction allows the rapid construction of 2-trifluoromethyl-3-acylindoles in a sequential C–C and C–O bond formation process under mild conditions.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA05967D
Reference51 articles.
1. R. D. Chambers , Fluorine in Organic Chemistry, 2nd edn, Blackwell, London, 2004
2. P. Kirsch , Modern Fluoroorganic Chemistry, Wiley-VCH, Weinheim, 2004
3. Fluorine, in Medicinal Chemistry And Chemical Biology, ed. I. Ojima, Wiley, Hoboken, 2009
4. Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
5. Synthetic Methods for Compounds Having CF3–S Units on Carbon by Trifluoromethylation, Trifluoromethylthiolation, Triflylation, and Related Reactions
Cited by 31 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Pd-Catalyzed Deacylative [4 + 1] Annulation of N-Arylimidoyl Chlorides with β-Keto Esters Leading to 2-Fluoroalkyl Indoles;The Journal of Organic Chemistry;2024-09-10
2. Recent Advancements in Trifluoromethylation Strategies for Indoles, Oxindoles and Indolines;ChemistrySelect;2024-08-22
3. Radical Cyclization-Initiated Difunctionalization Reactions of Alkenes and Alkynes;Molecules;2024-05-29
4. F‐Tag Induced Acyl Shift in the Photochemical Cyclization of o‐Alkynylated N‐Alkyl‐N‐acylamides to Indoles**;European Journal of Organic Chemistry;2023-02-22
5. Photochemical radical cyclization reactions with imines, hydrazones, oximes and related compounds;Chemical Society Reviews;2021
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3