Copper-catalyzed selective oxidation of hydrazones through C(sp3)–H functionalization

Author:

Shen Jiabin12,Jiang Xiaoying23,Wu Haifeng12,Xu Jun2,Zhu Qing1ORCID,Zhang Pengfei2ORCID

Affiliation:

1. Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou 310014, China

2. College of Material, Chemistry and Chemical Engineering, Key Laboratory of Organosilicon Chemistry and Material Technology, Ministry of Education, Hangzhou Normal University, Hangzhou, 311121, Zhejiang, People's Republic of China

3. College of Chemistry and Chemical Engineering, Central south University, Changsha, 410083, P.R. China

Abstract

A simple and mild protocol for copper-catalyzed oxidation of hydrazones at the α-position has been reported. Various substrates are compatible, providing the corresponding products in moderate to good yields.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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