Curse or Cure? A Perspective on the Developability of Aldehydes as Active Pharmaceutical Ingredients
Author:
Affiliation:
1. Genentech, 1 DNA Way, South San Francisco, 94080 California, United States
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c01177
Reference213 articles.
1. Aldehyde Sources, Metabolism, Molecular Toxicity Mechanisms, and Possible Effects on Human Health
2. Metabolic activation and drug toxicity
3. Biotransformation Reactions of Five-Membered Aromatic Heterocyclic Rings
4. Hypersensitivity reactions during therapy with the nucleoside reverse transcriptase inhibitor abacavir
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