Micellar nanoformulation of lipophilized bortezomib: high drug loading, improved tolerability and targeted treatment of triple negative breast cancer
Author:
Affiliation:
1. Biomedical Polymers Laboratory
2. and Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application
3. College of Chemistry
4. Chemical Engineering and Materials Science
5. Soochow University
Abstract
Lipophilization of bortezomib with pinanediol enables efficacious drug loading and targeted tumor chemotherapy with reduction-sensitive self-crosslinked micellar systems.
Funder
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering,General Chemistry,General Medicine
Link
http://pubs.rsc.org/en/content/articlepdf/2017/TB/C7TB01297G
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