Highly diastereoselective synthesis of an octahydro-1H-cyclpenta[c]pyridine skeleton via a Pd/Au-relay catalyzed reaction of (Z)-1-iodo-1,6-diene and alkyne-Reference-Cited by-同舟云学术

Highly diastereoselective synthesis of an octahydro-1H-cyclpenta[c]pyridine skeleton via a Pd/Au-relay catalyzed reaction of (Z)-1-iodo-1,6-diene and alkyne

Published:2022 Issue:12 Volume:9 Page:3186-3191
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Chi Xiaochen¹,Xia Tong¹,Yang Yi¹,Cao Tong¹,Zhang Daopeng¹,Liu Hui¹^ORCID

Affiliation:

1. School of Chemistry & Chemical Engineering, Shandong University of Technology, 266 West Xincun Road, Zibo 255049, P. R. China

Abstract

The octahydro-1H-cyclopenta[c]pyridine skeletons exist in a broad spectrum of bioactive natural products, and the development of efficient and convenient protocols to construct this skeleton remains a challenging task.

Funder

National Natural Science Foundation of China

Colleges and Universities Youth Innovation Technology Program of Shandong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/QO/D2QO00233G

Reference41 articles.

1. Total Synthesis of (−)-Incarvilline, (+)-Incarvine C, and (−)-Incarvillateine

2. Total synthesis of (−)-incarvilline