Synthesis of 10H-indolo[1,2-a]indol-10-ones via palladium-catalyzed C–H bond activation and difluorocarbene transfer-Reference-Cited by-同舟云学术

Synthesis of 10H-indolo[1,2-a]indol-10-ones via palladium-catalyzed C–H bond activation and difluorocarbene transfer

Published:2022 Issue:41 Volume:20 Page:8120-8124
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Hu Chengxian¹,Mou Dan¹,Zhang Xi¹,Fu Ying¹^ORCID,Huo Congde¹^ORCID,Du Zhengyin¹^ORCID

Affiliation:

1. Key Laboratory of Eco-functional Polymer Materials of the Ministry of Education, College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070, P. R. China

Abstract

A Pd-catalyzed annulation between 1-(2-iodophenyl)-1H-indoles and sodium difluorochloroacetate has been developed to synthesize 10H-indolo[1,2-a]indol-10-one derivatives via C–H bond activation and difluorocarbene transfer.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Gansu Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/OB/D2OB01493A

Reference45 articles.

1. Practical Methodologies for the Synthesis of Indoles

2. Development of an Enantiodivergent Strategy for the Total Synthesis of (+)- and (−)-Dragmacidin F from a Single Enantiomer of Quinic Acid