Insulin dimer dissociation and unfolding revealed by amide I two-dimensional infrared spectroscopy
Author:
Affiliation:
1. Department of Chemistry
2. Massachusetts Institute of Technology
3. Cambridge
4. USA
Abstract
A structurally sensitive probe of the monomer/dimer equilibrium of insulin was developed using 2DIR spectroscopy and interpreted using calculated spectra.
Publisher
Royal Society of Chemistry (RSC)
Subject
Physical and Theoretical Chemistry,General Physics and Astronomy
Link
http://pubs.rsc.org/en/content/articlepdf/2010/CP/B923515A
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