Molecular iodine-catalysed oxidative CO–C(alkyl) bond cleavage of aryl/heteroaryl alkyl ketones: an efficient strategy to access fused polyheterocycles

Author:

Mani Geeta Sai123,Rao Ayanampudi Venkata Subba453,Tangella Yellaiah453,Sunkari Satish453,Sultana Faria453,Namballa Hari Krishna123,Shankaraiah Nagula123ORCID,Kamal Ahmed12345ORCID

Affiliation:

1. Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research

2. Hyderabad-500037

3. India

4. Division of Medicinal Chemistry and Pharmacology, CSIR-Indian Institute of Chemical Technology

5. Hyderabad-500007

Abstract

An efficient molecular iodine-catalysed one-pot strategy has been accomplished for the construction of various fused heterocycles under metal and oxidant free conditions.

Funder

Department of Chemicals and Petrochemicals, Ministry of Chemicals and Fertilizers

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Reference66 articles.

1. Coinage Metal-Assisted Synthesis of Heterocycles

2. Transition Metal-Mediated Synthesis of Monocyclic Aromatic Heterocycles

3. L. D. Quin and J.Tyrell , Fundamentals of Heterocyclic Chemistry: Importance in Nature and in the Synthesis of Pharmaceuticals , John Wiley & Sons Inc. , New York , 2010

4. Metalated Heterocycles and Their Applications in Synthetic Organic Chemistry

5. Modern advances in heterocyclic chemistry in drug discovery

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