Molecular iodine-catalysed oxidative CO–C(alkyl) bond cleavage of aryl/heteroaryl alkyl ketones: an efficient strategy to access fused polyheterocycles
Author:
Affiliation:
1. Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research
2. Hyderabad-500037
3. India
4. Division of Medicinal Chemistry and Pharmacology, CSIR-Indian Institute of Chemical Technology
5. Hyderabad-500007
Abstract
An efficient molecular iodine-catalysed one-pot strategy has been accomplished for the construction of various fused heterocycles under metal and oxidant free conditions.
Funder
Department of Chemicals and Petrochemicals, Ministry of Chemicals and Fertilizers
Science and Engineering Research Board
Publisher
Royal Society of Chemistry (RSC)
Subject
Materials Chemistry,General Chemistry,Catalysis
Link
http://pubs.rsc.org/en/content/articlepdf/2018/NJ/C8NJ03417F
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3. L. D. Quin and J.Tyrell , Fundamentals of Heterocyclic Chemistry: Importance in Nature and in the Synthesis of Pharmaceuticals , John Wiley & Sons Inc. , New York , 2010
4. Metalated Heterocycles and Their Applications in Synthetic Organic Chemistry
5. Modern advances in heterocyclic chemistry in drug discovery
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