Discovery of 1,2,4-triazole-1,3-disulfonamides as dual inhibitors of mitochondrial complex II and complex III-Reference-Cited by-同舟云学术

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Discovery of 1,2,4-triazole-1,3-disulfonamides as dual inhibitors of mitochondrial complex II and complex III

Published:2015 Issue:9 Volume:39 Page:7281-7292
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Cheng Hua¹²³⁴⁵,Shen Yan-Qing¹²³⁴⁵,Pan Xia-Yan⁶⁷⁸⁹¹⁰,Hou Yi-Ping⁶⁷⁸⁹¹⁰,Wu Qiong-You¹²³⁴⁵,Yang Guang-Fu¹²³⁴⁵

Affiliation:

1. Key Laboratory of Pesticide & Chemical Biology

2. Ministry of Education

3. College of Chemistry

4. Central China Normal University

5. Wuhan 430079

6. Department of Pesticide Science

7. College of Plant Protection

8. Nanjing Agricultural University

9. Nanjing 210095

10. P. R. China

Abstract

1,2,4-Triazole-1,3-disulfonamide derivatives as dual function inhibitors of mitochondrial complex II (SQR) and complex III (cyt bc₁) were discovered.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2015/NJ/C5NJ00215J

Reference35 articles.

1. Structural basis for the mechanism of electron bifurcation at the quinol oxidation site of the cytochrome bc 1 complex

2. The Cytochrome bc1 Complex: Function in the Context of Structure

3. Inhibitor binding changes domain mobility in the iron-sulfur protein of the mitochondrial bc1 complex from bovine heart

4. A Structural Perspective on Mechanism and Function of the Cytochrome bc 1 Complex

5. Structure and Function of Cytochrome bc Complexes

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