Microfluidic assessment of mechanical cell damage by extensional stress-Reference-Cited by-同舟云学术

Microfluidic assessment of mechanical cell damage by extensional stress

Published:2016 Issue:1 Volume:16 Page:96-103
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Bae Young Bok¹²³⁴,Jang Hye Kyeong⁵⁶⁷⁸⁴,Shin Tae Hwan⁹¹⁰¹¹⁴¹²,Phukan Geetika⁹¹⁰¹¹⁴,Tran Thanh Tinh⁵⁶⁷⁸⁴,Lee Gwang⁹¹⁰¹¹⁴,Hwang Wook Ryol⁵⁶⁷⁸⁴,Kim Ju Min¹²³⁴¹³

Affiliation:

1. Department of Energy Systems Research

2. Ajou University

3. Suwon 443-749

4. Republic of Korea

5. School of Mechanical Engineering

6. Research Center for Aircraft Parts Technology

7. Gyeongsang National University

8. Jinju 660-701

9. Department of Physiology and Department of Biomedical Sciences

10. Ajou University School of Medicine

11. Suwon 443-721

12. Department of Molecular Science and Technology

13. Department of Chemical Engineering

Abstract

A novel microfluidic method to accurately assess the cell damage under controlled extensional stress, simulating the bubble bursting process in bioreactors.

Funder

Ministry of Science, ICT and Future Planning

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2016/LC/C5LC01006C

Reference35 articles.

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2. Fluid-mechanical damage of animal cells in bioreactors

3. Animal cell cultures: recent achievements and perspectives in the production of biopharmaceuticals

4. R. Godoy-Silva , C.Berdugo and J. J.Chalmers, Aeration, Mixing and Hydrodynamics, Animal Cell Bioreactors, in Encyclopedia of Industrial Biotechnology: Bioprocess, Bioseparation, and Cell Technology, ed. M. C. Flickinger, John Wiley & Sons, Inc., 1st edn, 2009, pp. 1–27

5. Oxygen transfer and mixing in mechanically agitated airlift bioreactors

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