Bioreactivity of a novel poly(epsilon-caprolactone) nanocapsule containing atrazine with human lung alveolar epithelial cells

Author:

Moore Amber J. S.1ORCID,Dean Lareb S. N.12ORCID,Yam Aiken N. K.1ORCID,de Lima Renata3ORCID,Fraceto Leonardo F.4ORCID,Tetley Teresa D.12ORCID

Affiliation:

1. Lung Cell Biology, Airways Disease, National Heart and Lung Institute, Imperial College London, London, UK

2. The National Institute for Health Research Health Protection Research Unit (NIHR HPRU), Health Impact of Environmental Hazards at King's College London in partnership with Public Health England (PHE) in collaboration with Imperial College London, London, UK

3. LABiToN − Laboratory for Evaluation of Bioactivity and Toxicology of Nanomaterials, University of Sorocaba, São Paulo, Brazil

4. São Paulo State University (UNESP), Institute of Science and Technology of Sorocaba, Laboratory of Environmental Nanotechnology, Sorocaba, São Paulo, Brazil

Abstract

Nanoencapsulation of pesticide atrazine improves efficacy. However, this study discovered adverse bioreactivity in alveolar type 1 epithelial cells (a major recipient of inhaled nano-sized particles), following exposure to nanoencapsulated atrazine.

Funder

Fundação de Amparo à Pesquisa do Estado de São Paulo

National Institute for Health Research Health Protection Research Unit

Publisher

Royal Society of Chemistry (RSC)

Subject

General Environmental Science,Materials Science (miscellaneous)

Reference90 articles.

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5. Mobility of atrazine in soils of a wastewater irrigated maize field

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