Novel styryl-thiazole hybrids as potential anti-Alzheimer's agents-Reference-Cited by-同舟云学术

Novel styryl-thiazole hybrids as potential anti-Alzheimer's agents

Published:2023 Issue:11 Volume:14 Page:2315-2326
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

Gouleni Niki¹,Di Rienzo Annalisa²,Yılmaz Ahmet³,Selvitopi Harun⁴,Arslan Mehmet Enes³,Mardinoglu Adil⁵⁶,Turkez Hasan⁷,Di Stefano Antonio²,Vassiliou Stamatia¹,Cacciatore Ivana²^ORCID

Affiliation:

1. Laboratory of Organic Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Athens, Greece

2. Department of Pharmacy, “G. D'Annunzio” University of Chieti-Pescara, 66100, Chieti Scalo, CH, Italy

3. Department of Molecular Biology and Genetics, Faculty of Science, Erzurum Technical University, 25050, Erzurum, Turkey

4. Department of Mathematics, Faculty of Sciences, Erzurum Technical University, 25050, Erzurum, Turkey

5. Science for Life Laboratory, KTH-Royal Institute of Technology, SE-17121 Stockholm, Sweden

6. Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London SE1 9RT, UK

7. Department of Medical Biology, Faculty of Medicine, Atatürk University, Erzurum, Turkey

Abstract

Novel styryl-thiazole hybrids (6a–p) was rationally designed, synthesized, and evaluated by the multi-target-directed ligands strategy as potential candidates for the treatment of Alzheimer's disease.

Funder

Ministero dell'Università e della Ricerca

National and Kapodistrian University of Athens

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/MD/D3MD00308F

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