Boron-based hybrids as novel scaffolds for the development of drugs with neuroprotective properties-Reference-Cited by-同舟云学术

Boron-based hybrids as novel scaffolds for the development of drugs with neuroprotective properties

Published:2021 Issue:11 Volume:12 Page:1944-1949
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

Cacciatore Ivana¹^ORCID,Turkez Hasan²,Di Rienzo Annalisa¹,Ciulla Michele¹,Mardinoglu Adil³⁴,Di Stefano Antonio¹

Affiliation:

1. Department of Pharmacy, University “G. d'Annunzio” of Chieti-Pescara, via dei Vestini 31, 66100 Chieti Scalo, CH, Italy

2. Faculty of Science, Basic Medical Sciences, Medical Biology Department, Ataturk University, 25240 Yakutiye, Erzurum, Turkey

3. Science for Life Laboratory, KTH, Royal Institute of Technology, 24075 Stockholm, Sweden

4. Centre for Host-Microbiome Interactions, Dental Institute, King's College London, London SE1 9RT, UK

Abstract

Boron-based hybrids, containing a lipoyl group as an antioxidant moiety, as multi-target ligands against oxidative stress and Aβ-neurotoxicity, and for inhibition of acetylcholinesterase in an experimental in vitro model of Alzheimer's disease.

Funder

Ministero dell’Istruzione, dell’Università e della Ricerca

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/MD/D1MD00177A

Reference22 articles.

1. Therapeutic potential of boron-containing compounds

2. Boron-containing compounds: chemico-biological properties and expanding medicinal potential in prevention, diagnosis and therapy

3. Bortezomib – First Therapeutic Proteasome Inhibitor for Cancer Therapy: A Review of Patent Literature

4. The safety of current and emerging therapies for multiple myeloma

5. Structural Basis and Binding Kinetics of Vaborbactam in Class A β-Lactamase Inhibition

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