Rapid, quantitative therapeutic screening for Alzheimer's enzymes enabled by optimal signal transduction with transistors-Reference-Cited by-同舟云学术

Rapid, quantitative therapeutic screening for Alzheimer's enzymes enabled by optimal signal transduction with transistors

Published:2020 Issue:8 Volume:145 Page:2925-2936
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Le Son T.¹²³⁴⁵,Morris Michelle A.⁶⁷³⁴⁵,Cardone Antonio⁸⁹³⁴⁵,Guros Nicholas B.⁶⁷³⁴⁵,Klauda Jeffery B.¹⁰¹¹¹²⁵^ORCID,Sperling Brent A.¹³¹⁴³⁴⁵,Richter Curt A.¹²³⁴⁵,Pant Harish C.¹⁵¹⁶¹⁷⁵,Balijepalli Arvind⁶⁷³⁴⁵^ORCID

Affiliation:

1. Alternative Computing Group

2. Nanoscale Device Characterization Division

3. National Institute of Standards and Technology

4. Gaithersburg

5. USA

6. Biophysics Group

7. Microsystems and Nanotechnology Division

8. Information Systems Group

9. Software and Systems Division

10. Department of Chemical and Biomolecular Engineering

11. University of Maryland

12. College Park

13. Chemical Process and Nuclear Measurements Group

14. Chemical Sciences Division

15. National Institute of Neurological Disorders and Stroke

16. National Institutes of Health

17. Bethesda

Abstract

Commercially sourced silicon field-effect transistors enable sensitive measurements of small therapeutic molecules that regulate enzymes implicated in Alzheimer's disease.

Funder

Physical Measurement Laboratory

Information Technology Laboratory

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/AN/C9AN01804B

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