Synthesis of arene-functionalized fused heterocyclic scaffolds <i>via</i> a regioselective cascade 1,4-conjugate addition/5-<i>exo-dig</i> annulation strategy-Reference-Cited by-同舟云学术

Synthesis of arene-functionalized fused heterocyclic scaffolds via a regioselective cascade 1,4-conjugate addition/5-exo-dig annulation strategy

Published:2023 Issue:46 Volume:21 Page:9159-9172
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

He Xinwei¹^ORCID,Wang Demao¹,Liu Yanan¹,Wu Mengdi¹,Kong Yangzilin¹,Tang Qiang¹,Wang Yiping¹,Fan Chenli²,Shang Yongjia¹^ORCID

Affiliation:

1. Key Laboratory of Functional Molecular Solids, Ministry of Education, Anhui Laboratory of Molecule-Based Materials (State Key Laboratory Cultivation Base), College of Chemistry and Materials Science, Anhui Normal University, Wuhu 241000, P.R. China

2. School of Material Engineering, Wuhu Institute of Technology, Wuhu, 241002, People's Republic of China

Abstract

We have developed an efficient method for the synthesis of highly sterically congested 3-phenolic furo[3,2-c]pyran-4-ones and furo[3,2-c]pyridin-4(5H)-ones by the formation of a furan ring from readily available starting materials in a single step.

Funder

University Natural Science Research Project of Anhui Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D3OB01572F

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3. Phellifuropyranone A: A New Furopyranone Compound Isolated from Fruit Bodies of Wild Phellinus linteus

4. Furan‐Based o‐ Quinodimethanes by Gold‐Catalyzed Dehydrogenative Heterocyclization of 2‐(1‐Alkynyl)‐2‐alken‐1‐ones: A Modular Entry to 2,3‐Furan‐Fused Carbocycles

5. Phelligridins C−F: Cytotoxic Pyrano[4,3-c][2]benzopyran-1,6-dione and Furo[3,2-c]pyran-4-one Derivatives from the Fungus Phellinus igniarius