Furo[3,2-c]coumarins carrying carbon substituents at C-2 and/or C-3. Isolation, biological activity, synthesis and reaction mechanisms
Author:
Affiliation:
1. Instituto de Química Rosario (IQUIR, CONICET-UNR)
2. Facultad de Ciencias Bioquímicas y Farmacéuticas – Universidad Nacional de Rosario
3. S2002LRK Rosario
4. Argentina
Abstract
The isolation, synthesis and biological activity of naturally occurring furo[3,2-c] coumarins carrying carbon substituents at C-2 and/or C-3, is discussed. Synthetic approaches toward the properly functionalized heterocyclic motif are also presented.
Funder
Fondo para la Investigación Científica y Tecnológica
Consejo Nacional de Investigaciones Científicas y Técnicas
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/RA/D0RA06930B
Reference317 articles.
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2. Synthesis of Coumarins with 3:4-Fused Ring Systems and their Physiological Activity
3. Furocoumarins in Medicinal Chemistry. Synthesis, Natural Occurrence and Biological Activity
4. Syntheses of furo[3,4-c]coumarins and related furyl coumarin derivatives via intramolecular Wittig reactions
5. First synthesis of furo[3,4-c]coumarins
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