Insulin fibrillation control by specific zinc binding sites-Reference-Cited by-同舟云学术

Insulin fibrillation control by specific zinc binding sites

Published:2021 Issue:24 Volume:8 Page:5251-5259
ISSN:2052-1553
Container-title:Inorganic Chemistry Frontiers
language:en
Short-container-title:Inorg. Chem. Front.

Author:

Ben-Shushan Shira¹²^ORCID,Miller Yifat¹²^ORCID

Affiliation:

1. Department of Chemistry, Ben-Gurion University of the Negev, P.O. Box 653, Beér Sheva 84105, Israel

2. Ilse Katz Institute for Nanoscale Science and Technology, Ben-Gurion University of the Negev, Beér-Sheva 84105, Israel

Abstract

Herein, we present for the first time a study that identifies the morphology of full-length insulin fibrils in the absence and in the presence of Zn2+ ions.

Funder

Israel Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/QI/D1QI01054A

Reference55 articles.

1. Proteostasis of Islet Amyloid Polypeptide: A Molecular Perspective of Risk Factors and Protective Strategies for Type II Diabetes

2. Localized Amyloidosis at the Site of Repeated Insulin Injection in a Diabetic Patient

3. Stability and Performance of Rapid-Acting Insulin Analogs Used for Continuous Subcutaneous Insulin Infusion: A Systematic Review

4. Insulin-derived amyloidosis

5. The protofilament structure of insulin amyloid fibrils

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