Insulin glycation coupled with liposomal lipid peroxidation and microglial cell death

Author:

Sabokdast Manijheh12345,Habibi-Rezaei Mehran12345,Poursasan Najmeh6345,Sabouni Farzaneh7845,Ferdousi Maryam12345,Azimzadeh-Irani Effat12345,Moosavi-Movahedi Ali Akbar63459

Affiliation:

1. School of Biology

2. College of Science

3. University of Tehran

4. Tehran

5. Iran

6. Institute of Biochemistry and Biophysics

7. Department of Basic Sciences of Biotechnology

8. National Institute of Genetic Engineering and Biotechnology

9. Center of Excellence in Biothermodynamics

Abstract

Type 2 diabetes is characterized jointly by hyperglycemia and hyperinsulinemia, which make insulin prone to glycation then fibrillation.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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