Biosynthesis and bioactivities of microbial genotoxin colibactins-Reference-Cited by-同舟云学术

Biosynthesis and bioactivities of microbial genotoxin colibactins

Published:2022 Issue:5 Volume:39 Page:991-1014
ISSN:0265-0568
Container-title:Natural Product Reports
language:en
Short-container-title:Nat. Prod. Rep.

Author:

Tang Jian-Wei¹²,Liu Xin¹²,Ye Wei¹³,Li Zhong-Rui⁴,Qian Pei-Yuan¹²^ORCID

Affiliation:

1. Department of Ocean Science, Hong Kong Branch of Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), The Hong Kong University of Science and Technology, Kowloon, Hong Kong, China

2. Southern Marine Science and Engineering Guangdong Laboratory, Guangzhou 511458, China

3. State Key Laboratory of Applied Microbiology Southern China, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou 510070, China

4. Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA

Abstract

This review provides an update on biosynthesis and bioactivities of colibactin(s), the long-sought genotoxins produced by the pks island of Escherichia coli.

Funder

National Key Research and Development Program of China

Southern Marine Science and Engineering Guangdong Laboratory

Cancer Research Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/NP/D1NP00050K

Reference122 articles.

1. Immune System, Microbiota, and Microbial Metabolites: The Unresolved Triad in Colorectal Cancer Microenvironment