Association of Pre-diagnostic Antibody Responses to Escherichia coli and Bacteroides fragilis Toxin Proteins with Colorectal Cancer in a European Cohort

Author:

Butt Julia1,Jenab Mazda2ORCID,Werner Jill1,Fedirko Veronika3,Weiderpass Elisabete4,Dahm Christina C.3,Tjønneland Anne56,Olsen Anja57,Boutron-Ruault Marie-Christine8,Rothwell Joseph A.8,Severi Gianluca89ORCID,Kaaks Rudolf10,Turzanski-Fortner Renée10,Aleksandrova Krasimira11,Schulze Matthias1213,Palli Domenico14,Pala Valeria15,Panico Salvatore16,Tumino Rosario17,Sacerdote Carlotta18,Bueno-de-Mesquita Bas19202122,Van Gils Carla H.23ORCID,Gram Inger Torhild24,Lukic Marko25,Sala Núria26,Sánchez Pérez María José27282930,Ardanaz Eva313233,Chirlaque María-Dolores3435,Palmquist Richard36,Löwenmark Thyra36,Travis Ruth C37,Heath Alicia38,Cross Amanda J38,Freisling Heinz2,Zouiouich Semi2,Aglago Elom2,Waterboer Tim1,Hughes David J.39ORCID

Affiliation:

1. Infections and Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany

2. International Agency for Research on Cancer (IARC-WHO), Lyon, France

3. Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA

4. Department of Public Health, Aarhus University, Aarhus, Denmark

5. Exposome and Heredity Team, CESP (Centre de Recherche en Epidemiologie et Santé des Populations), Diet, Genes and Environment, Nutrition and Biomarkers (NAB), Danish Cancer Society Research Center, Copenhagen, Denmark

6. Department of Public Health, University of Copenhagen, Denmark

7. Department of Public Health, University of Aarhus, Denmark

8. Cesp (Umr1018), Médecine Université Paris-Saclay, Inserm, Gustave Roussy, Villejuif, France

9. Department of Statistics, Computer Science and Applications (DISIA), University of Florence, Italy

10. Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany

11. Department of Nutrition and Gerontology, German Institute of Human Nutrition Potsdam-Rehbruecke, Germany

12. Department of Molecular Epidemiology, German Institute of Human Nutrition, Potsdam-Rehbruecke, Nuthetal, Germany

13. Institute of Nutritional Science, University of Potsdam, Nuthetal, Germany

14. Institute for Cancer Research, Prevention and Clinical Network - ISPRO, Florence, Italy

15. Epidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy

16. Dipartimento Di Medicina Clinica E Chirurgia, Federico II University, Naples, Italy

17. Cancer Registry and Histopathology Department, Provincial Health Authority (ASP 7), Ragusa, Italy

18. Unit of Cancer Epidemiology, Città Della Salute E Della Scienza University-Hospital, Turin, Italy

19. Former Senior Scientist, Dept. For Determinants of Chronic Diseases (DCD), National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands

20. Former Associate Professor, Department of Gastroenterology and Hepatology, University Medical Centre, Utrecht, The Netherlands

21. Former Visiting Professor, Dept. Of Epidemiology and Biostatistics, The School of Public Health, Imperial College London, London, UK

22. Former Academic Icon/visiting Professor, Dept. Of Social & Preventive Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

23. Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands

24. Department of Community Medicine, University of Tromsø, the Arctic University of Norway, Tromsø, Norway

25. Department of Community Medicine, UiT, The Arctic University of Norway, Tromsø, Norway

26. Unit of Nutrition, Environment and Cancer, Cancer Epidemiology Research Program and Translational Research Laboratory, Catalan Institute of Oncology (ICO), Biomedical Research Institute (IDIBELL), Barcelona, Spain

27. Escuela Andaluza De Salud Pública (EASP), Granada, Spain

28. Instituto De Investigación Biosanitaria ibs.GRANADA, Granada, Spain

29. Centro De Investigación Biomédica En Red De Epidemiología Y Salud Pública (CIBERESP), Madrid, Spain

30. Department of Preventive Medicine and Public Health, University of Granada, Granada, Spain

31. Navarra Public Health Institute, Pamplona, Spain

32. IdiSNA, Navarra Institute for Health Research, Pamplona, Spain

33. CIBER Epidemiology and Public Health CIBERESP, Madrid, Spain

34. Department of Epidemiology, Regional Health Council, IMIB-Arrixaca, Murcia University, Murcia, Spain

35. CIBER in Epidemiology and Public Health (CIBERESP), Madrid, Spain

36. Department of Medical Biosciences, Pathology, Umeå University, Ireland

37. Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK

38. Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK

39. Cancer Biology and Therapeutics Group, School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin, Dublin, Ireland

Funder

European Cooperation in Science and Technology

Publisher

Informa UK Limited

Subject

Infectious Diseases,Microbiology (medical),Gastroenterology,Microbiology

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