Rapid identification of human muscle disease with fibre optic Raman spectroscopy

Author:

Alix James J. P.12ORCID,Plesia Maria1,Lloyd Gavin R.3,Dudgeon Alexander P.45ORCID,Kendall Catherine A.4,Hewamadduma Channa126,Hadjivassiliou Marios6,McDermott Christopher J.12,Gorman Gráinne S.78ORCID,Taylor Robert W.78ORCID,Shaw Pamela J.12ORCID,Day John C. C.9ORCID

Affiliation:

1. Sheffield Institute for Translational Neuroscience, University of Sheffield, UK

2. Neuroscience Institute, University of Sheffield, UK

3. Phenome Centre Birmingham, University of Birmingham, UK

4. Biophotonics Research Unit, Gloucestershire Hospitals NHS Foundation Trust, UK

5. Biomedical Spectroscopy, School of Physics and Astronomy, University of Exeter, UK

6. Department of Neurology, Sheffield Teaching Hospitals NHS Foundation Trust, UK

7. Wellcome Centre for Mitochondrial Research, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK

8. NHS Highly Specialised Service for Rare Mitochondrial Disorders, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK

9. Interface Analysis Centre, School of Physics, University of Bristol, UK

Abstract

We demonstrate the use of fibre optic Raman spectroscopy for the rapid identification of muscle disorders.

Funder

National Institute for Health Research

Wellcome Trust Centre for Mitochondrial Research

NIHR Newcastle Biomedical Research Centre

Medical Research Council

Lily Foundation

Academy of Medical Sciences

Wellcome Trust

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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