Graphene oxide is degraded by neutrophils and the degradation products are non-genotoxic-Reference-Cited by-同舟云学术

Graphene oxide is degraded by neutrophils and the degradation products are non-genotoxic

Published:2018 Issue:3 Volume:10 Page:1180-1188
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Mukherjee Sourav P.¹²³⁴⁵,Gliga Anda R.¹²³⁴⁵,Lazzaretto Beatrice¹²³⁴⁵,Brandner Birgit⁶⁷⁸⁵⁹,Fielden Matthew¹⁰¹¹¹²⁵⁹,Vogt Carmen¹⁰¹¹¹²⁵⁹,Newman Leon¹³¹⁴¹⁵¹⁶¹⁷,Rodrigues Artur F.¹³¹⁴¹⁵¹⁶¹⁷,Shao Wenting¹⁸¹⁹²⁰²¹,Fournier Philip M.¹⁸¹⁹²⁰²¹,Toprak Muhammet S.¹⁰¹¹¹²⁵⁹^ORCID,Star Alexander¹⁸¹⁹²⁰²¹^ORCID,Kostarelos Kostas¹³¹⁴¹⁵¹⁶¹⁷,Bhattacharya Kunal¹²³⁴⁵,Fadeel Bengt¹²³⁴⁵^ORCID

Affiliation:

1. Nanosafety & Nanomedicine Laboratory

2. Division of Molecular Toxicology

3. Institute of Environmental Medicine

4. Karolinska Institutet

5. Stockholm

6. Unit for Chemistry

7. Materials and Surfaces

8. SP Technical Research Institute of Sweden

9. Sweden

10. Department of Applied Physics

11. School of Engineering Sciences

12. Royal Institute of Technology

13. Nanomedicine Laboratory

14. Faculty of Medical & Human Sciences and National Graphene Institute

15. University of Manchester

16. Manchester

17. UK

18. Department of Chemistry

19. University of Pittsburgh

20. Pittsburgh

21. USA

Abstract

Graphene oxide (GO) undergoes neutrophil myeloperoxidase (MPO) dependent degradation and the degradation products are non-genotoxic for human lung cells.

Funder

National Institute of Environmental Health Sciences

European Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2018/NR/C7NR03552G

Reference38 articles.

1. Science and technology roadmap for graphene, related two-dimensional crystals, and hybrid systems

2. Biological interactions of carbon-based nanomaterials: From coronation to degradation