Folic acid and deoxycholic acid derivative modified Fe3O4 nanoparticles for efficient pH-dependent drug release and multi-targeting against liver cancer cells-Reference-Cited by-同舟云学术

Folic acid and deoxycholic acid derivative modified Fe3O4 nanoparticles for efficient pH-dependent drug release and multi-targeting against liver cancer cells

Published:2021 Issue:63 Volume:11 Page:39804-39812
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Wang Xiaoyu¹,Ma Qing¹,Wen Chaochao²,Gong Tao¹,Li Jing²,Liang Wenting²^ORCID,Li Meining¹,Wang Yuyao¹,Guo Rui¹

Affiliation:

1. Department of Biochemistry and Molecular Biology, Shanxi Medical University, Taiyuan 030001, China

2. Institute of Environmental Science, Department of Chemistry, Shanxi University, Taiyuan 030006, China

Abstract

A nano-drug carrier, FDCA-FA-MNPs was constructed by modifying Fe3O4 magnetic nanoparticles (MNPs) with formyl deoxycholic acid (FDCA) and folic acid (FA) with double-targeting, pH-triggered drug release and excellent tumor cell killing efficiency.

Funder

National Natural Science Foundation of China

Shanxi Provincial Key Research and Development Project

Shanxi Scholarship Council of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D1RA05874F

Reference40 articles.

1. Pediatric Hepatocellular Carcinoma