Unveiling sequential late-stage methyltransferase reactions in the meleagrin/oxaline biosynthetic pathway-Reference-Cited by-同舟云学术

Unveiling sequential late-stage methyltransferase reactions in the meleagrin/oxaline biosynthetic pathway

Published:2018 Issue:35 Volume:16 Page:6450-6459
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Newmister Sean A.¹²³⁴,Romminger Stelamar¹²³⁴^ORCID,Schmidt Jennifer J.¹²³⁴,Williams Robert M.⁵⁶⁷⁴⁸,Smith Janet L.¹²³⁴⁹^ORCID,Berlinck Roberto G. S.¹⁰¹¹¹²¹³^ORCID,Sherman David H.¹²³⁴¹⁴^ORCID

Affiliation:

1. Life Sciences Institute

2. University of Michigan

3. Ann Arbor

4. USA

5. Department of Chemistry

6. Colorado State University

7. Fort Collins

8. University of Colorado Cancer Center

9. Department of Biological Chemistry

10. Instituto de Química de São Carlos

11. Universidade de São Paulo

12. CEP 13.560-970 São Carlos

13. Brazil

14. Department of Medicinal Chemistry

Abstract

Enzymatic activity and crystal structures of the methyltransferases involved in the biosynthesis of fungal natural products meleagrin and oxaline.

Funder

Fundação de Amparo à Pesquisa do Estado de São Paulo

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Division of Chemistry

National Institutes of Health

National Institute of General Medical Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/OB/C8OB01565A

Reference40 articles.

1. Prenylated indole derivatives from fungi: structure diversity, biological activities, biosynthesis and chemoenzymatic synthesis

2. Biocatalysts for Natural Product Biosynthesis

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