Balancing polymer hydrophobicity for ligand presentation and siRNA delivery in dual function CXCR4 inhibiting polyplexes-Reference-Cited by-同舟云学术

Balancing polymer hydrophobicity for ligand presentation and siRNA delivery in dual function CXCR4 inhibiting polyplexes

Published:2015 Issue:7 Volume:3 Page:1114-1123
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Wang Y.¹²³⁴⁵,Li J.¹²³⁴⁵,Chen Y.¹²³⁴⁵,Oupický D.¹²³⁴⁵

Affiliation:

1. Center for Drug Delivery and Nanomedicine

2. Department of Pharmaceutical Sciences

3. University of Nebraska Medical Center

4. Omaha

5. USA

Abstract

Dual-function polycations capable of simultaneously antagonizing CXCR4 receptors and delivering anti-PLK1 siRNA to achieve combination anticancer effect.

Funder

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2015/BM/C5BM00003C

Reference52 articles.

1. Rational siRNA design for RNA interference

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5. Design and development of polymers for gene delivery

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