Progress and problems with the use of viral vectors for gene therapy
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics(clinical),Genetics,Molecular Biology
Link
http://www.nature.com/articles/nrg1066.pdf
Reference120 articles.
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2. Clark, K., Liu, X., McGrath, J. P. & Johnson, P. R. Highly purified recombinant adeno-associated virus vectors are biologically active and free of detectable helper and wild-type viruses. Hum. Gene Ther. 10, 1031–1039 (1999).
3. Green, A. et al. A new scalable method for the purification of recombinant adenovirus vectors. Hum. Gene Ther. 13, 1921–1934 (2002).
4. Kay, M. A. & Woo, S. L. Gene therapy for metabolic disorders. Trends Genet. 10, 253–257 (1994).
5. Lowenstein, P. Why are we doing so much cancer gene therapy? Disentangling the scientific basis from the origins of gene therapy. Gene Ther. 4, 755–756 (1997).
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