Novel Pt(ii) complexes with modified aroyl-hydrazone Schiff-base ligands: synthesis, cytotoxicity and action mechanism
Author:
Affiliation:
1. State Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources
2. Ministry of Science and Technology of China
3. Guangxi Normal University
4. Guilin
5. China
6. China Pharmaceutical University
7. Nanjing
Abstract
The complex-induced apoptosis of cancer cells via: (1) the mitochondrial pathway; (2) inserting into and cleaving DNA; and (3) inhibiting telomerase.
Funder
National Natural Science Foundation of China
Natural Science Foundation of Guangxi Province
National Basic Research Program of China
Publisher
Oxford University Press (OUP)
Subject
Metals and Alloys,Biochemistry,Biomaterials,Biophysics,Chemistry (miscellaneous)
Link
http://pubs.rsc.org/en/content/articlepdf/2019/MT/C9MT00193J
Reference80 articles.
1. Clinical Perspectives on Platinum Resistance
2. Cisplatin resistance: Preclinical findings and clinical implications
3. Phase II trial of bevacizumab and satraplatin in docetaxel-pretreated metastatic castrate-resistant prostate cancer
4. Activating Platinum Anticancer Complexes with Visible Light
5. Phase II Study of Picoplatin As Second-Line Therapy for Patients With Small-Cell Lung Cancer
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