Novel Pt(ii) complexes with modified aroyl-hydrazone Schiff-base ligands: synthesis, cytotoxicity and action mechanism-Reference-Cited by-同舟云学术

Novel Pt(ii) complexes with modified aroyl-hydrazone Schiff-base ligands: synthesis, cytotoxicity and action mechanism

Published:2019 Issue:11 Volume:11 Page:1847-1863
ISSN:1756-5901
Container-title:Metallomics
language:en
Short-container-title:Metallomics

Author:

Deng Jungang¹²³⁴⁵^ORCID,Yu Ping¹²³⁴⁵,Zhang Zhenlei¹²³⁴⁵,Zhang Juzheng¹²³⁴⁵,Zhewen Sun¹²³⁴⁵,Cai Meiling¹²³⁴⁵,Yuan Haoliang⁶⁷⁵,Liang Hong¹²³⁴⁵,Yang Feng¹²³⁴⁵

Affiliation:

1. State Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources

2. Ministry of Science and Technology of China

3. Guangxi Normal University

4. Guilin

5. China

6. China Pharmaceutical University

7. Nanjing

Abstract

The complex-induced apoptosis of cancer cells via: (1) the mitochondrial pathway; (2) inserting into and cleaving DNA; and (3) inhibiting telomerase.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guangxi Province

National Basic Research Program of China

Publisher

Oxford University Press (OUP)

Subject

Metals and Alloys,Biochemistry,Biomaterials,Biophysics,Chemistry (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2019/MT/C9MT00193J

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