Tailor-made gemcitabine prodrug nanoparticles from well-defined drug–polymer amphiphiles prepared by controlled living radical polymerization for cancer chemotherapy
Author:
Affiliation:
1. Tianjin Key Laboratory of Biomaterial Research
2. Institute of Biomedical Engineering
3. Chinese Academy of Medical Science and Peking Union Medical College
4. Tianjin, China
5. School of Chemical Engineering and Technology
6. Tianjin University
Abstract
Novel prodrug nanoparticles with a tailorable high drug payload and in vivo anti-cancer activity assembled from well-defined gemcitabine–polymer conjugate amphiphiles prepared by RAFT polymerization are presented.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering,General Chemistry,General Medicine
Link
http://pubs.rsc.org/en/content/articlepdf/2014/TB/C3TB21558J
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