Competitive DNA binding of Ru(bpy)2dppz2+ enantiomers studied with isothermal titration calorimetry (ITC) using a direct and general binding isotherm algorithm-Reference-Cited by-同舟云学术

Competitive DNA binding of Ru(bpy)2dppz2+ enantiomers studied with isothermal titration calorimetry (ITC) using a direct and general binding isotherm algorithm

Published:2018 Issue:12 Volume:20 Page:7920-7930
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Mårtensson Anna K. F.¹²³⁴^ORCID,Lincoln Per¹²³⁴

Affiliation:

1. Department of Chemistry and Chemical Engineering

2. Chalmers University of Technology

3. SE-41296 Gothenburg

4. Sweden

Abstract

A simple algorithm allowing for binding isotherm calculations of almost any level of complexity is demonstrated here in a competitive ITC setting with enantiopure Ru-bpy intercalating into AT-DNA.

Funder

Vetenskapsrådet

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

http://pubs.rsc.org/en/content/articlepdf/2018/CP/C7CP03184J

Reference33 articles.

1. Modeling complex equilibria in isothermal titration calorimetry experiments: Thermodynamic parameters estimation for a three-binding-site model

2. Lifetime Heterogeneity of DNA-Bound dppz Complexes Originates from Distinct Intercalation Geometries Determined by Complex–Complex Interactions

3. Binding of Ru(terpyridine)(pyridine)dipyridophenazine to DNA studied with polarized spectroscopy and calorimetry

4. A generalized McGhee–von Hippel method for the cooperative binding of different competing ligands to an infinite one-dimensional lattice

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