Binding of Ru(terpyridine)(pyridine)dipyridophenazine to DNA studied with polarized spectroscopy and calorimetry
Author:
Affiliation:
1. Department of Chemical and Biological Engineering
2. Chalmers University of Technology
3. SE-41296 Gothenburg
4. Sweden
Abstract
Achiral Ru(tpy)(py)dppz2+ intercalated into DNA has similar intermolecular interactions as opposite enantiomers of its structural isomer, the “light-switch” complex Ru(bpy)2dppz2+.
Funder
Vetenskapsrådet
Publisher
Royal Society of Chemistry (RSC)
Subject
Inorganic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/DT/C4DT02642J
Reference38 articles.
1. Cisplatin: From DNA damage to cancer chemotherapy
2. Tris(phenanthroline)ruthenium(II): stereoselectivity in binding to DNA
3. Binding modes and base specificity of tris(phenanthroline)ruthenium(II) enantiomers with nucleic acids: tuning the stereoselectivity
4. Characterization of dipyridophenazine complexes of ruthenium(II): The light switch effect as a function of nucleic acid sequence and conformation
5. DNA binding of .DELTA.- and .LAMBDA.-[Ru(phen)2DPPZ]2+
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