Chemodivergent synthesis of N-(pyridin-2-yl)amides and 3-bromoimidazo[1,2-a]pyridines from α-bromoketones and 2-aminopyridines

Author:

Liu Yanpeng12345,Lu Lixue1234,Zhou Haipin6784,Xu Feijie1234,Ma Cong910111213ORCID,Huang Zhangjian1234ORCID,Xu Jinyi1234ORCID,Xu Shengtao1234

Affiliation:

1. State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry

2. China Pharmaceutical University

3. Nanjing 210009

4. China

5. Department of Chemistry

6. College of Materials & Chemical Engineering

7. Chuzhou University

8. Chuzhou 239000

9. State Key Laboratory of Chemical Biology and Drug Discovery

10. Department of Applied Biology and Chemical Technology

11. The Hong Kong Polytechnic University

12. Kowloon

13. P. R. China

Abstract

N-(Pyridin-2-yl)amides and 3-bromoimidazo[1,2-a]pyridines were synthesized respectively from α-bromoketones and 2-aminopyridine under different reaction conditions.

Funder

National Natural Science Foundation of China

China Pharmaceutical University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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